Seoul National University
Lab of T cell Differentiation
Understanding T cell development, tissue immunity, and immune regulation
Research FIELDS
Immunology
Alopecia Areata
Alopecia areata is an autoimmune disease characterized by aberrant Th1-immune responses causing hair loss. our laboratory studies the role of T cells in disease pathogenesis to uncover immune mechanisms and develop new therapeutic strategies.
Innate T cells
Invariant natural killer T (iNKT), mucosal-associated invariant T (MAIT), and γδ T cells are innate T cells. Innate T cells acquire memory phenotypes in the thymus and share similar biological characteristics such as tissue residency and early effector function. We investigate how innate T cells develop, differentiate, and regulate immune responses.
Thymic B cells
As key components of adaptive immunity, B cells build our body's antibody repertoire. Thymic B cells are a rare population localized in the thymus; however, their precise role and impact on infectious diseases and autoimmunity remain poorly understood. To bridge this gap, our research investigates the phenotypic characteristics of thymic B cells and how they relate to immune regulation
MEMBER
연구실 연구원 소개
You Jeong Lee, MD-ph.D.
Sae Bom Lee, ph.D
Myeong-Seok Lee
Sihyung Joo
Sang-Hyeok Ji
Tae-Hyun Kim
Jun Hur
Suhjeon Shin
Yoonji Lee
Junghwan Choi
Research
Published papers
Dual Roles of MAIT Cells in the Tumor Microenvironment: Implications for Cancer Immunity and Therapy
The Role of Innate T Cells in Inflammatory Disorders in Asthma and Chronic Rhinosinusitis
Human MAIT cells undergo clonal selection and expansion during thymic maturation and aging
NOTICE
연구실 공지사항
-
2026-07-29
-
2026-07-29
-
2026-07-07
-
2026-07-03
-
2026-06-26